Terbinafine: Safe, Effective Therapy for NAFLD Liver Cancer
Terbinafine, a Novel Therapeutic Drug in the Treatment of Liver Cancer
Tags: The Chinese University of Hong Kong, Hong Kong, Healthcare & Lifesciences
This technology repurposes terbinafine, an FDA-approved antifungal drug, as a novel treatment for non-alcoholic fatty liver disease (NAFLD)-associated liver cancer. By inhibiting the oncogenic factor SQLE, terbinafine has shown effectiveness in animal models, significantly suppressing tumor growth and improving survival without side effects. This therapeutic approach offers potential applications in treating liver cancer linked to NAFLD. It presents a promising solution for a condition that currently lacks targeted therapy.
IP Type or Form Factor: Patent Granted; Material
TRL: 4 - minimum viable product built in lab
Industry or Tech Area: Pharmaceutical Engineering; Biotechnology
