Teixobactin Analogues Revolutionize Antibiotic Resistance
Novel Analogues of Teixobactin and the Synthetic Method
Tags: The University of Hong Kong, Hong Kong, Healthcare & Lifesciences
This technology introduces a novel method for the total chemical synthesis of teixobactin and its analogues, overcoming previous challenges in production. The new analogues exhibit enhanced antibacterial activities and target multi-drug-resistant bacteria with a distinct mechanism of action. Applications include developing next-generation antibiotics to combat the global rise in antimicrobial resistance. The invention addresses a critical medical need with potential products for advanced therapeutics. Protected by a US provisional patent, this innovation offers a scalable solution for antibiotic development.
IP Type or Form Factor: Patent Pending; Process & Method; Platform
TRL: 3 - proof of concept with needs validated
Industry or Tech Area: Pharmaceutical Engineering; Biotechnology