Stem Cell-Derived Osteochondral Interface for Tissue Repair
In Vitro Generation of an Osteochondral Interface
Tags: The University of Hong Kong, Hong Kong, Healthcare & Lifesciences
This technology presents a novel in vitro method to generate an osteochondral interface, resembling physiological conditions, using a multi-layered co-culture system. The approach utilizes stem cells to create a 3D structure with hypertrophic chondrocytes, calcium phosphate deposits, and specific collagens, making it ideal for tissue engineering and cell-based therapy applications. The technology addresses the lack of effective solutions for repairing complex bone-and-cartilage interfaces, such as in articular cartilage or intervertebral discs. Completed animal studies validate its potential for clinical use, and it is open for licensing under PCT Application No: PCT/CN2011/000988. This innovation opens new markets in tissue repair and regenerative medicine.
IP Type or Form Factor: Patent Pending; Material; Process & Method
TRL: 4 - minimum viable product built in lab
Industry or Tech Area: Biotechnology; Healthcare Provider
