Stable Palladium (II) Complexes Boost Anti-Cancer Therapies
Palladium (II) Complexes in Anti-cancer
Tags: The University of Hong Kong, Hong Kong, Healthcare & Lifesciences
This technology introduces palladium (II) N-heterocyclic carbene (NHC) complexes as potent anti-cancer agents, overcoming traditional stability issues in physiological conditions. These complexes exhibit high in vitro and in vivo stability, potent cytotoxicity against cancer cells, and effective inhibition of EGFR signaling pathways while inducing mitochondrial dysfunction. Applications include the development of innovative anti-cancer drugs leveraging this platform technology. The technology addresses the challenges of palladium complexes by enhancing stability and therapeutic efficacy. Patented under PCT, this innovation has the potential to revolutionize cancer treatment.
IP Type or Form Factor: Patent Pending; Material; Platform
TRL: 4 - minimum viable product built in lab
Industry or Tech Area: Pharmaceutical Engineering; Biotechnology
