Peptide Mimetic Therapy: Cardiac Repair Without Fibrosis
Novel Peptide Mimetic For Heart Repair
Tags: The University of Sydney, Australia, Healthcare & Lifesciences
This innovation introduces peptide mimetic compounds inspired by Platelet-Derived Growth Factor (PDGF) that promote cardiac repair while minimizing fibrosis. Designed to mimic a specific region of the PDGF-B chain, these compounds enhance vascularity and healing in damaged heart tissue, with applications in post-myocardial infarct recovery, cardiac function restoration, and heart failure management. The peptide conjugated with albumin increases in vivo activity and effectiveness, offering a minimally invasive alternative to current treatments. This technology addresses the limitations of existing cardiac therapies by enabling precise tissue repair without adverse effects. Protected by PCT/AU2023/050866, it holds significant potential for advancing cardiology treatments.
IP Type or Form Factor: Patent Pending; Material; Platform
TRL: 3 - proof of concept with needs validated
Industry or Tech Area: Healthcare Provider; Biotechnology
