OPTIClear: Fast, Low-Cost Tissue Clearing for 3D Histology
OPTIClear: A Novel Tissue Clearing Agent for Next Generation Histology
Tags: The University of Hong Kong, Hong Kong, Healthcare & Lifesciences
OPTIClear is a novel tissue clearing agent that enhances optical transparency without altering tissue structure, enabling high-resolution, 3D mapping for histological studies. Its low-viscosity and low-osmolality composition ensures faster clearing with minimal tissue damage, making it effective for both fresh and archival formalin-fixed tissues. Applications include 3D visualization of cellular structures in brain, spine, and kidney tissues, supporting advanced histology and cytology research. Prototypes have shown compatibility with fluorescent labeling and electron microscopy. Patented globally and awarded a Gold Medal at the International Exhibition of Inventions Geneva, this innovation sets a new standard for next-generation histology.
IP Type or Form Factor: Patent Pending; Process & Method; Material
TRL: 4 - minimum viable product built in lab
Industry or Tech Area: Biotechnology; Diagnostics & Screening
