Novel Reagent Boosts Purity, Yield of Extracellular Vesicles
A Reagent for Improved Purity and Yield of Biofluid-Derived Extracellular Vesicles (EVs)
Tags: The University of Queensland, Australia, Healthcare & Lifesciences
"Reagent A" is a novel chemical that enhances the purity and yield of extracellular vesicles (EVs) by effectively removing lipoprotein contaminants from biofluids, preserving EV morphology, and being compatible with standard purification methods. Its introduction into existing workflows allows for simpler, faster, and more efficient purification compared to traditional, multiple-step processes. This advancement holds promise for significantly improving therapeutic and diagnostic applications involving EVs, including in biomarker-based diagnostics and cell-free therapies. The technology represents a pivotal improvement in the isolation of biofluid-derived EVs, addressing the critical challenge of lipoprotein contamination.
IP Type or Form Factor: Patent Pending; Process & Method; Material
TRL: 5 - prototype ready for testing in intended environment
Industry or Tech Area: Biotechnology; Diagnostics & Screening
