Novel Peptides Identified for Antibiotics Resistance
Two Cationic Peptides as Potent Antibiotics Killing Antibiotics-Resistance Gram-Negative Bacteria
Tags: The Hong Kong University of Science and Technology, Hong Kong, Healthcare & Lifesciences
This innovation identifies two new peptide antibiotics, brevicidine and laterocidine, effective against drug-resistant Gram-negative bacteria, a major public health threat. Analyzing thousands of bacterial genomes revealed these compounds, showing promise in combating pathogens like Pseudomonas aeruginosa and colistin-resistant E. coli. The peptides also demonstrate efficacy in mouse models, indicating potential for development into treatments. This method could lead to breakthroughs in fighting infections that current antibiotics can't handle.
IP Type or Form Factor: Patent Granted; Process & Method
TRL: Not specified
Industry or Tech Area: Public Health & Universal Healthcare; Pharmaceutical Engineering
