Novel Antibiotic Self Repairs Kidney, Stops Fibrosis
World's First Antibiotic Treatment That Enables Damaged Kidneys to Regenerate
Tags: SingHealth Duke-NUS, Singapore, Healthcare & Lifesciences
Researchers at Duke-NUS Medical School and the National Heart Centre Singapore have developed the first antibiotic treatment that promotes self-repair in damaged organs, including the kidneys, lungs, and liver. This innovation targets Interleukin 11 (IL11), a protein that causes fibrosis, which is linked to organ damage and failure. Experiments in mice showed kidney recovery within three months without side effects by inhibiting IL11. The technology is patented and licensed to Boehringer-Ingelheim for phase I clinical trials starting in 2024. This breakthrough offers a potential non-invasive treatment for organ fibrosis, currently lacking in the market.
IP Type or Form Factor: Patent Granted; Platform
TRL: 3 - proof of concept with needs validated
Industry or Tech Area: Biotechnology; Pharmaceutical Engineering
