Mimicking Macromolecular Interfaces to Design New Drugs
New Strategy for Development of Drug Molecules
Tags: IIT Delhi, India, Healthcare & Lifesciences
Researchers at IIT Delhi, led by Prof. V. Haridas, have developed a new strategy for designing potential drug molecules to treat various diseases. The team collaborated with experts from THSTI and Kusuma School of Biological Sciences. Their approach involves mimicking macromolecular interfaces with uniquely shaped small molecules using tools from Organic Chemistry and Biophysics. This method simplifies the design of inhibitors for Protein-Protein Interactions (PPI). Applications include treatment for Japanese Encephalitis Virus and protein aggregation diseases like Alzheimer's, with potential for retroviral infections.
IP Type or Form Factor: Process & Method; Platform
TRL: 4 - minimum viable product built in lab
Industry or Tech Area: Biotechnology; Pharmaceutical Engineering
