Gpx4 Gene Discovery Enhances Cold Resistance for Medical Use
Syrian Hamsters Reveal Genetic Secret to Hibernation
Tags: Hokkaido University, Japan, Healthcare & Lifesciences
Researchers at Hokkaido University identified a gene in Syrian hamsters, Gpx4, which helps mammalian cells survive extreme cold by reducing harmful lipid peroxide radicals. This discovery highlights the potential of applying hibernation mechanisms to human health, particularly in organ preservation and hypothermia therapies. By overexpressing Gpx4, human cells showed increased resistance to cold conditions. The study advances our understanding of cold resistance in mammals and offers applications in medical preservation technologies. The research represents a significant step toward harnessing natural hibernation mechanisms for medical purposes.
IP Type or Form Factor: Discovery & Research
TRL: 3 - proof of concept with needs validated
Industry or Tech Area: Biotechnology; Healthcare Provider
