Enhance Brain Cancer Treatment with Nanoformulation
Cure for Brain Cancer Gets Promising Results in Pre-Clinical Trials
Tags: IIT Delhi, India, Healthcare & Lifesciences, Science & Exploration
Researchers at IIT Delhi have developed a novel nanoformulation called Immunosomes, combining a CD40 agonist antibody with the small molecule inhibitor RRX-001, to treat glioblastoma. In mice, this treatment eradicated tumors and generated a long-lasting immune response, preventing tumor recurrence upon re-challenge. This approach aims to enhance treatment efficacy and reduce toxicity associated with CD40 agonist antibodies, offering new hope for glioblastoma patients. Applications include improved outcomes and long-term protection against brain tumors. These promising results motivate further research and clinical trials in humans.
IP Type or Form Factor: Platform; Process & Method; Material
TRL: 4 - minimum viable product built in lab
Industry or Tech Area: Biotechnology; Nanotechnology
