Directed Evolution System for Advanced Biomolecules
Novel System For Directed Evolution In Mammalian Cells
Tags: The University of Sydney, Australia, Healthcare & Lifesciences
This novel system enables directed evolution (DE) in mammalian cells, addressing limitations of existing DE methods by using virus-like particles (VLPs) to evolve target biomolecules. It facilitates error-prone replication within mammalian environments, making it highly relevant for applications in drug development, diagnostics, and personalized medicine. The system efficiently generates biomolecules with desirable traits, offering breakthroughs in genetic therapies and protein engineering. Applications include evolving biomolecules for drug discovery, targeted genetic therapies, and novel diagnostics. Protected by a provisional patent, this technology represents a significant advancement in healthcare and biotechnology research.
IP Type or Form Factor: Patent Pending; Platform
TRL: 3 - proof of concept with needs validated
Industry or Tech Area: Biotechnology; Pharmaceutical Engineering